Cerebro: Mammillary body The hypophysis cerebri in position. Shown in sagittal section. (Label "corpus mamillare" at right.) Coronal section of brain through intermediate mass of third ventricle. (Label "corpus mamillare" at bottom.) Latin corpus mamillare Gray's subject #188 813 Part of Midbrain Components medial mammillary nucleus lateral mammillary nucleus Artery Vein BrainInfo/UW hier-395 MeSH A08.186.211.730.385.357.362.500 The mammillary bodies (mamillary bodies) are a pair of small round bodies, located on the undersurface of the brain, that form part of the limbic system. They are located at the ends of the anterior arches of the fornix. They consist of two groups of nuclei, the medial mammillary nuclei and the lateral mammillary nuclei. Neuroanatomists have often categorized the mammillary bodies as part of the hypothalamus. Contenido 1 Connections 2 Function 3 Patología 4 Imágenes adicionales 5 Referencias 6 External links Connections They are connected to other parts of the brain (as shown in the schematic, below left), and act as a relay for impulses coming from the amygdalae and hippocampi, via the mamillo-thalamic tract to the thalamus. This circuit, from amygdalae to mammillary bodies, and then on to the thalamus, is part of the larger 'Papez circuit'. Function They, along with the anterior and dorsomedial nuclei in the thalamus, are involved with the processing of recognition memory. They are believed to add the element of smell to memories. Pathology The mammillary bodies are parts of the brain known to be significantly damaged by untreated Obstructive Sleep Apnea Hypoxia,and associated with deficiency of thiamine. Researchers, en 2008, also noted visible abnormalities in the mammillary bodies of individuals with Obstructive Sleep Apnea. Damage to the mammillary bodies due to thiamine deficiency is implied in pathogenesis of Wernicke-Korsakoff syndrome. Symptoms include impaired memory, also called anterograde amnesia, suggesting that the mammillary bodies may be important for memory. Lesions of the medial dorsal and anterior nuclei of the thalami and lesions of the mammillary bodies are commonly involved in amnesic syndromes in humans. Additional images Brain Human brainstem anterior view 2 description.JPG Human brainstem anterior view Gehirn, basal - beschriftet lat.svg Basal view of a human brain Mammillary body.gif Mammillary body shown in red(animation) References ↑ http://www.cf.ac.uk/psych/resources/vann2004.pdf Reference for the two groups of nuclei (not for the text before). ↑ M.B. Carpenter and J. Sutin: Human Neuroanatomy (8ª edición) 1983 ↑ - "The Auditory System: Anatomy and Maturation" at www.conradsimon.org ↑ Duprez T, Serieh B, Raftopoulos C (1 Enero 2005). Absence of memory dysfunction after bilateral mammillary body and mammillothalamic tract electrode implantation: preliminary experience in three patients. AJNR. American journal of neuroradiology 26 (1): 195–7; author reply 197–8. External links Vann S, Aggleton J (2004). The mammillary bodies: two memory systems in one?. Nat. Rev. Neurosci. 5 (1): 35–44. TheFreeDictionary.com - 'Mammillary body' Roche Lexicon - illustrated navigator, at Elsevier 13048.000-3 v·d·e Human brain: diencephalon (TA A14.1.08, Georgia 9.807) Epithalamus Surface Pineal body · Habenula · Habenular trigone · Habenular commissure Grey matter Pretectal area · Habenular nuclei · Subcommissural organ Thalamus Surface Stria medullaris of thalamus · Thalamic reticular nucleus · Taenia thalami Grey matter/ nuclei paired: AN · Ventral (VA/VL, VP/VPM/VPL) · Lateral (LD, LP, Pulvinar) · Metathalamus (MG, LG) midline: MD · Intralaminar (Centromedian) · Midline nuclear group · Interthalamic adhesion White matter Mammillothalamic fasciculus · Pallidothalamic tracts (Ansa lenticularis, Lenticular fasciculus, Thalamic fasciculus) · PCML (Medial lemniscus, Trigeminal lemniscus) · Spinothalamic tract · Lateral lemniscus · Dentatothalamic tract · Acoustic radiation · Optic radiation · Subthalamic fasciculus · Anterior trigeminothalamic tract Medullary laminae Hypothalamus Surface Median eminence/Tuber cinereum · Mammillary body · Infundibulum Grey matter Autonomic zones Anterior (parasympathetic/heat loss) · Posterior (sympathetic/heat conservation) Endocrine posterior pituitary: magnocellular/Paraventricular/Supraoptic (oxytocin/vasopressin) otro: parvocellular/Arcuate (dopamine/GHRH) · Preoptic (GnRH) · Suprachiasmatic (melatonin) Emotion Lateral (hunger) · Ventromedial (satiety) · Dorsomedial (rage) White matter afferent (SN → Medial forebrain bundle) · efferent (Mammillothalamic fasciculus → AN, Stria terminalis → Amygdala, Dorsal longitudinal fasciculus → SC) Pituitary Posterior is diencephalon, but anterior is glandular Subthalamus Subthalamic nucleus · Zona incerta Ventricular system: Third ventricle recesses: (Optic recess, Infundibular recess, Suprapineal recess, Pineal recess) Hypothalamic sulcus · Tela chorioidea of third ventricle Subfornical organ Apertures: Interventricular/Monro Posterior commissure Template:Papez circuit This page uses Creative Commons Licensed content from Wikipedia (ver autores).
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